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KMID : 1137820060270020064
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의공학회지
2006 Volume.27 No. 2 p.64 ~ p.72
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Patch-based Cortical Source Modeling for EEG/MEG Distributed Source Imaging: A Simulation Study
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Im Chang-Hwan
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Abstract
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The present study introduces a new cortical patch-based source model for EEG/MEG cortical source imaging to consider anatomical constraints more precisely. Conventional source models for EEG/MEG cortical source imaging have used coarse cortical surface mesh or sampled small number of vertices from fine surface mesh, and thus they failed to utilize full anatomical information which nowadays we can get with sub-millimeter modeling accuracy. Conventional ones placed a single dipolar source on each cortical patch and estimated its intensity by means of various inverse algorithms; whereas the suggested cortical patch-based model integrates whole cortical area to construct lead field matrix and estimates current density that is assumed to be constant in each cortical patch. We applied the proposed and conventional models to realistic EEG data and compared the results quantitatively. The quantitative comparisons showed that the proposed model can provide more precise spatial descriptions of neuronal source distribution.
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KEYWORD
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EEG, MEG, brain mapping, inverse problem, lead field construction, cortical source imaging
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